Products Details

Product Description

– Macimorelin (EP-1572), a GH secretagogue, is an orally active GHSR agonist. Macimorelin stimulates GH release. Macimorelin can be used in the research of adult growth hormone deficiency (AGHD), and Cancer anorexia-cachexia syndrome (CACS)[1][2][3].

Web ID

– HY-14820

Shipping

– Room temperature

Applications

– Metabolism-protein/nucleotide metabolism

Molecular Formula

– C26H30N6O3

References

– [1]Jose M Garcia, et al. Macimorelin as a Diagnostic Test for Adult GH Deficiency. J Clin Endocrinol Metab. 2018 Aug 1;103(8):3083-3093. |[2]An Buckinx, et al. Translational potential of the ghrelin receptor agonist macimorelin for seizure suppression in pharmacoresistant epilepsy. Eur J Neurol. 2021 Sep;28(9):3100-3112. |[3]Ali SA, Garcia JM. Randomized clinical trial of the novel oral ghrelin mimetic macimorelin in the treatment of cancer cachexia: study design and preliminary results. Endocr Rev. 2013;34:

CAS Number

– 381231-18-1

Molecular Weight

– 474.55

SMILES

– O=CN[C@@H](CC1=CNC2=CC=CC=C12)NC([C@H](NC(C(C)(N)C)=O)CC3=CNC4=CC=CC=C34)=O

Clinical Information

– Launched

Research Area

– Cancer; Endocrinology

Solubility

– 10 mM in DMSO

Target

– GHSR

Pathway

– GPCR/G Protein

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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