Download Files:
Products Details
Product Description
– M826 is a potent, selective and reversible non-peptide caspase-3 inhibitor with an IC50 value of 0.005 μM for enzymatic activity against caspase-3. M826 displays potent anti-apoptotic activity in animal models in vitro and in vivo. M826 can be used for nervous system diseases research[1].
Web ID
– HY-155612
Shipping
– Room temperature
Applications
– Neuroscience-Neurodegeneration
Molecular Formula
– C28H45N7O6
References
– [1]Han BH, et al. Selective, reversible caspase-3 inhibitor is neuroprotective and reveals distinct pathways of cell death after neonatal hypoxic-ischemic brain injury. J Biol Chem. 2002 Aug 16;277(33):30128-36.
Molecular Weight
– 575.70
SMILES
– O=C1N(C=C(N=C1NCC2=NON=C2C)C(C)(C)C)[C@H](C(N[C@H](C(CN(CCCCCC)C)=O)CC(O)=O)=O)CC
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Caspase
Pathway
– Apoptosis
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
