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M-110
Price range: 93 CAD through 149 CAD
Products Details
Product Description
– M-110 is a highly selective, ATP-competitive inhibitor of PIM kinases, showing a preference for PIM-3 (IC50=47 nM), and inhibits PIM-1 and PIM-2 with similar IC50s of 2.5 μM. M-110 also inhibits the proliferation of prostate cancer cell lines with IC50s of 0.6 to 0.9 μM.
Web ID
– T15830
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C22H28ClN5O3
References
– Chang M, et al.PIM kinase inhibitors downregulate STAT3(Tyr705) phosphorylation.Mol Cancer Ther. 2010 Sep;9(9):2478-87.
CAS Number
– 1395048-49-3
Molecular Weight
– C22H28ClN5O3
Compound Purity
– 0.983
SMILES
– CCC(=N/NC(=O)c1ccnc(NCCCN2CCOCC2)c1)c1ccc(Cl)cc1O
Target
– Others
Pathway
– Chromatin/Epigenetic|||JAK/STAT signaling
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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