LY2922470

SKU T15810-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 168 CAD through 2,704 CAD

Products Details

Product Description

– LY2922470 is a potent, selective G protein-coupled receptor 40 (GPR40) agonist, with EC50s of 7 nM for human GPR40, 1 nM for mouse GPR40 and 3 nM for rat GPR40, respectively. LY2922470 reduces glucose levels along and increases insulin and GLP-1 significantly.

Web ID

– T15810

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C28H29NO4S

References

– Hamdouchi C, et al. The Discovery, Preclinical, and Early Clinical Development of Potent and Selective GPR40 Agonists for the Treatment of Type 2 Diabetes Mellitus (LY2881835, LY2922083, and LY2922470). J Med Chem. 2016 Dec 22;59(24):10891-10916.

CAS Number

– 1423018-12-5

Molecular Weight

– C28H29NO4S

Compound Purity

– 0.9334

SMILES

– COc1cccc2CCCN(Cc3ccc(COc4ccc(cc4)[C@H](CC(O)=O)C#CC)s3)c12

Target

– Others

Pathway

– Endocrinology/Hormones|||GPCR/G Protein

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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