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LX-1031
$132 – $2,220
Products Details
Product Description
– LX-1031 is a potent, orally available tryptophan 5-hydroxylase (TPH) inhibitor that reduces serotonin (5-HT) synthesis peripherally.
Web ID
– HY-13041
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C28H25F3N4O4
References
– [1]Camilleri M. LX-1031, a tryptophan 5-hydroxylase inhibitor that reduces 5-HT levels for the potential treatment of irritable bowel syndrome. IDrugs. 2010 Dec;13(12):921-8.|[2]Camilleri M. LX-1031, a tryptophan 5-hydroxylase inhibitor, and its potential in chronic diarrhea associated with increased serotonin. Neurogastroenterol Motil. 2011 Mar;23(3):193-200.
CAS Number
– 945976-76-1
Molecular Weight
– 538.52
Compound Purity
– 98.32
SMILES
– NC1=NC(C2=CC=C(C=C2)C[C@@H](C(O)=O)N)=CC(O[C@H](C3=CC=C(C4=CC(OC)=CC=C4)C=C3)C(F)(F)F)=N1
Clinical Information
– Phase 2
Research Area
– Neurological Disease
Solubility
– DMSO : ≥ 34 mg/mL
Target
– Tryptophan Hydroxylase
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
