Lumiracoxib

$50$80

Products Details

Product Description

– Lumiracoxib is a potent,selective and orally active COX-2 inhibitor with a Ki value of 0.06 μM[1]. Lumiracoxib acts as a nonselective NSAID with anti-inflammatory, analgesic and antipyretic activities. Lumiracoxib can be used for osteoarthritis and bone cancer research[1][2].

Web ID

– HY-13507

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Applications

– Metabolism-protein/nucleotide metabolism

Molecular Formula

– C15H13ClFNO2

References

– [1]Ronald Esser, et al. Preclinical pharmacology of lumiracoxib: a novel selective inhibitor of cyclooxygenase-2. Br J Pharmacol. 2005 Feb;144(4):538-50.|[2]Alyson Fox, et al. Anti-hyperalgesic activity of the cox-2 inhibitor lumiracoxib in a model of bone cancer pain in the rat. Pain

CAS Number

– 220991-20-8

Molecular Weight

– 293.72

Compound Purity

– 99.65

SMILES

– O=C(O)CC1=CC(C)=CC=C1NC2=C(F)C=CC=C2Cl

Clinical Information

– Launched

Research Area

– Cancer; Metabolic Disease; Inflammation/Immunology

Solubility

– DMSO : 125 mg/mL (ultrasonic)

Target

– COX

Isoform

– COX-1;COX-2

Pathway

– Immunology/Inflammation

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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