LRRK2 inhibitor 1
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LRRK2 inhibitor 1

SKU T11878-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 109 CAD through 2,512 CAD

Products Details

Product Description

– LRRK2 inhibitor 1 is a selective and potent LRRK2 inhibitor with an IC50 of 13 nM.LRRK2 inhibitor 1 inhibits DCLK1 kinase with an IC50 value of 2.61 nM.

Web ID

– T11878

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C20H23N5O4

References

– Ding X, et al. Discovery of 4-ethoxy-7H-pyrrolo[2,3-d]pyrimidin-2-amines as potent, selective and orally bioavailable LRRK2 inhibitors. Bioorg Med Chem Lett. 2018 May 15;28(9):1615-1620.

CAS Number

– 1802525-61-6

Molecular Weight

– C20H23N5O4

Compound Purity

– 0.9973

SMILES

– CCOc1nc(Nc2ccc(cc2OC)C(=O)N2CCOCC2)nc2[nH]ccc12

Target

– Others

Pathway

– Cell Cycle/Checkpoint|||Autophagy

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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