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Products Details
Product Description
– LpxA-IN-1 is a novel UDP-N-acetylglucosamine acyltransferase (LpxA) inhibitor (IC50 2 nM) with activity against Pseudomonas aeruginosa (MIC 8 μg/mL).
Web ID
– HY-141838
Shipping
– Room temperature
Molecular Formula
– C21H11D7F3N5O3
References
– [1]Ryan MD, et al. Discovery of Novel UDP-N-Acetylglucosamine Acyltransferase (LpxA) Inhibitors with Activity against Pseudomonas aeruginosa. J Med Chem. 2021 Oct 14;64(19):14377-14425.
CAS Number
– 2822680-14-6
Molecular Weight
– 452.44
SMILES
– O=C(N(CC1=NN=C(N)O1)CC2=CC=C(C#N)C=C2F)C([2H])([2H])OC3=CC(F)=CC(F)=C3C([2H])([2H])C([2H])([2H])[2H]
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Bacterial
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
