Loureirin A
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Loureirin A

SKU T5S0896-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 109 CAD through 1,579 CAD

Products Details

Product Description

– Loureirin A has an inhibitory effect on platelet activation, perhaps through an impairment of PI3K/Akt signaling.Loureirin A negatively affects agonist-induced platelet aggregation such as collagen, collagen-related peptide (CRP), ADP and thrombin. Loureirin A activates Wnt/-catenin pathway and promotes hair follicle stem cells (FSCs)-seeded tissue-engineered skin to repair skin wound.The molecular mechanism of Loureirin A and Wnt signaling pathway mediated anti- hepatic fibrosis and anti- angiogenesis may involve down- regulation the expression of Frizzled- 4,inhibiting the synthesis and secretion of α- SMA,TGF- β1and the proliferation of HSCs.

Web ID

– T5S0896

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C17H18O4

References

– Hao H Z, He A D, Wang D C, et al. Antiplatelet activity of loureirin A by attenuating Akt phosphorylation: In vitro studies[J]. European Journal of Pharmacology, 2015, 746:63-69.

CAS Number

– 119425-89-7

Molecular Weight

– C17H18O4

Compound Purity

– 0.9984

SMILES

– COc1ccc(CCC(=O)c2ccc(O)cc2)c(OC)c1

Pathway

– PI3K/Akt/mTOR signaling|||Cytoskeletal Signaling

Product type

– Natural Product

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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