Lotilaner

SKU T15775-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 134 CAD through 3,712 CAD

Products Details

Product Description

– Lotilaner is a parasiticide. It is used as a potent non-competitive antagonist of insects GABACl receptors (IC50 of 23.84 nM for Drosophila melanogaster GABA receptor). It also has no effect on a dog GABAA receptor.

Web ID

– T15775

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C20H14Cl3F6N3O3S

References

– Lotilaner, et al. The novel isoxazoline ectoparasiticide lotilaner (Credelio™): a non-competitive antagonist specific to invertebrates γ-aminobutyric acid-gated chloride channels (GABACls). Parasit Vectors. 2017 Nov 1;10(1):530.

CAS Number

– 1369852-71-0

Molecular Weight

– C20H14Cl3F6N3O3S

Compound Purity

– 0.9956

SMILES

– Cc1cc(sc1C(=O)NCC(=O)NCC(F)(F)F)C1=NO[C@@](C1)(c1cc(Cl)c(Cl)c(Cl)c1)C(F)(F)F

Target

– Others

Pathway

– Microbiology/Virology|||Membrane transporter/Ion channel|||Neuroscience

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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