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Lotiglipron
$80 – $1,370
Products Details
Product Description
– Lotiglipron (PF-07081532) is an orally active GLP-1R agonist. Lotiglipron reduces glucose and body weight, and can be used for research of Type 2 diabetes mellitus (T2DM)[1].
Web ID
– HY-153865
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Molecular Formula
– C31H31ClN4O5
References
– [1]Buckeridge C, et al. Once-daily oral small molecule GLP-1R agonist PF-07081532 reduces glucose and body weight within 4-6 weeks in adults with type 2 diabetes and non-diabetic adults with obesity. Hybrid 58th EASD Annual Meeting; Sept 19–23, 2022 (abstr 114).
CAS Number
– 2401892-75-7
Molecular Weight
– 575.05
Compound Purity
– 99.68
SMILES
– C[C@@]1(C2=CC=C(C=N2)Cl)OC3=C(C4CCN(CC4)CC(N(C5=C6)C[C@@H]7CCO7)=NC5=CC=C6C(O)=O)C=CC=C3O1
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease
Solubility
– DMSO : 125 mg/mL (ultrasonic)
Target
– GCGR
Pathway
– GPCR/G Protein
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
