Lotamilast
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Lotamilast

SKU T3987-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 46 CAD through 1,021 CAD

Products Details

Product Description

– Lotamilast (RVT-501) is a phosphodiesterase 4 (PDE-4) inhibitor (IC50: 2.8 nM) potentially for the treatment of atopic dermatitis.

Web ID

– T3987

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C26H24N4O5

References

– Nemoto O., et al. Effect of topical phosphodiesterase 4 inhibitor E6005 on Japanese children with atopic dermatitis: Results from a randomized, vehicle-controlled exploratory trial. J Dermatol. 2016 Aug;43(8):881-7.

CAS Number

– 947620-48-6

Molecular Weight

– C26H24N4O5

Compound Purity

– 0.9844

SMILES

– CNc1nc(-c2cccc(NC(=O)c3ccc(cc3)C(=O)OC)c2)c2cc(OC)c(OC)cc2n1

Pathway

– Metabolism

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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