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Londamocitinib
$670 – $5,500
Products Details
Product Description
– Londamocitinib (AZD4604; JAK1-IN-7) is a Janus-associated kinase 1 (JAK1) inhibitor extracted from patent WO2018134213A1, Example 63, has an anti-inflammatory effect[1].
Web ID
– HY-126294
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C28H31F2N7O4S
References
– [1]NILSSON, Karl, Magnus, et al. Jak1 selective inhibitors. WO2018134213A1.
CAS Number
– 2241039-81-4
Molecular Weight
– 599.65
Compound Purity
– 98.98
SMILES
– FC1=C(S(C)(=O)=O)C=CC=C1NC2=NC(C3=CNC4=C3C=CC=C4NC([C@@H](COC)N5CCN(C)CC5)=O)=C(F)C=N2
Clinical Information
– Phase 1
Research Area
– Inflammation/Immunology
Solubility
– DMSO : 71.43 mg/mL (ultrasonic)
Target
– JAK
Isoform
– JAK1
Pathway
– Epigenetics;JAK/STAT Signaling;Protein Tyrosine Kinase/RTK;Stem Cell/Wnt
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
