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Products Details
Product Description
– LmNADK1-IN-1 (compound MC1) is an inhibitor of nicotinamide adenine dinucleotide kinases (NADK1) from
L. monocytogenes with a Ki value of 54 nM. LmNADK1-IN-1 can be used for the research of bacterial infection[1]. LmNADK1-IN-1 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Web ID
– HY-151936
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C27H33N13O9S
References
– [1]Clément DA, et al. Synthesis and structure-activity relationship studies of original cyclic diadenosine derivatives as nanomolar inhibitors of NAD kinase from pathogenic bacteria. Eur J Med Chem. 2022 Nov 23;246:114941.
Molecular Weight
– 715.70
SMILES
– NC1=NC=NC(N2[C@H](O3)[C@H](O)[C@H](O)[C@H]3CNS(CCN4)(=O)=O)=C1N=C2C#CCN(C[C@@H]5[C@@H](O)[C@@H](O)[C@H](N6C=NC(C6=NC=N7)=C7N)O5)CC4=O
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Bacterial
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
