LMD-009

$380$650

Products Details

Product Description

– LMD-009 is a selective CCR8 nonpeptide agonist. LMD-009 mediates chemotaxis, inositol phosphate accumulation, and calcium release in high potencies with EC50s from 11 to 87 nM[1].

Web ID

– HY-121885

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Applications

– Metabolism-protein/nucleotide metabolism

Molecular Formula

– C29H33N3O3

References

– [1]Jensen PC, et al. Molecular interaction of a potent nonpeptide agonist with the chemokine receptor CCR8. Mol Pharmacol. 2007 Aug;72(2):327-40.

CAS Number

– 950195-51-4

Molecular Weight

– 471.59

Compound Purity

– 99.76

SMILES

– O=C1NCN(CCC2=CC=CC=C2)C13CCN(CC4=CC=CC(OC5=CC=CC=C5OC)=C4)CC3

Clinical Information

– No Development Reported

Research Area

– Metabolic Disease; Endocrinology

Solubility

– DMSO : 250 mg/mL (ultrasonic)

Target

– CCR

Isoform

– CCR8

Pathway

– GPCR/G Protein;Immunology/Inflammation

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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