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Linifanib
Price range: 69 CAD through 1,373 CAD
Products Details
Product Description
– Linifanib (AL-39324) (ABT-869) is a novel, potent ATP-competitive VEGFR/PDGFR inhibitor for KDR (IC50: 4 nM), CSF-1R (IC50: 3 nM), Flt-1/3 (IC50: 3/4 nM) and PDGFRβ (IC50: 66 nM). Linifanib may exhibit potent antiproliferative and apoptotic effects on tumor cells whose proliferation is dependent on mutant kinases, such as FMS-related tyrosine kinase receptor-3 (FLT3).
Web ID
– T2514
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C21H18FN5O
References
– Albert DH, et al. Mol Cancer Ther, 2006, 5(4), 995-1006.
CAS Number
– 796967-16-3
Molecular Weight
– C21H18FN5O
Compound Purity
– 0.9824
SMILES
– Cc1ccc(F)c(NC(=O)Nc2ccc(cc2)-c2cccc3[nH]nc(N)c23)c1
Pathway
– Apoptosis|||Tyrosine Kinase/Adaptors|||Angiogenesis|||Autophagy
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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