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Limaprost

$132$1,980

Products Details

Product Description

– Limaprost (OP1206) is a PGE1 analogue and a potent and orally active vasodilator. Limaprost increases blood flow and inhibits platelet aggregation. Limaprost pain relief, has antianginal effects, and can be used for ischaemic symptoms research[1][2].

Web ID

– HY-B0683

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Applications

– COVID-19-immunoregulation

Molecular Formula

– C22H36O5

References

– [1]Tsuboi T, et al. Pharmacological evaluation of OP 1206, a prostaglandin E1 derivative, as an antianginal agent. Arch Int Pharmacodyn Ther. 1980 Sep;247(1):89-102.|[2]Swainston Harrison T, et al. Limaprost. Drugs. 2007;67(1):109-18; discussion 119-20.|[3]Murata K, et al. PGE1 Attenuates IL-1β-induced NGF Expression in Human Intervertebral Disc Cells. Spine (Phila Pa 1976). 2016 Jun;41(12):E710-6.

CAS Number

– 74397-12-9

Molecular Weight

– 380.52

Compound Purity

– 99.91

SMILES

– O=C(O)/C=C/CCCC[C@@H]1[C@@H](/C=C/[C@@H](O)C[C@@H](C)CCCC)[C@H](O)CC1=O

Clinical Information

– Launched

Research Area

– Inflammation/Immunology; Cardiovascular Disease

Solubility

– DMSO : ≥ 40 mg/mL

Target

– PGE synthase

Pathway

– Immunology/Inflammation

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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