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Levofloxacin
$66 – $92
Products Details
Product Description
– Levofloxacin ((-)-Ofloxacin) is an orally active antibiotic and is active against both Gram-positive and Gram-negative bacteria. Levofloxacin inhibits the DNA gyrase and topoisomerase IV. Levofloxacin can be used for chronic periodontitis, airway inflammation and BK Viremia research. Levofloxacin shows anti-orthopoxvirus activity[1][2][3][4][5].
Web ID
– HY-B0330
Storage Temperature
– 4°C (Powder, protect from light)
Shipping
– Room Temperature
Applications
– COVID-19-anti-virus
Molecular Formula
– C18H20FN3O4
Citations
– Antibiotics (Basel). 2022, 11(2), 192.|Antimicrob Agents Chemother. 2021 Feb 17;65(3):e01921-20.|Clin Chem. 2019 Dec;65(12):1522-1531. |Nat Commun. 2022 Mar 2;13(1):1116.
References
– [1]Drlica K, et al. DNA gyrase, topoisomerase IV, and the 4-quinolones. Microbiol Mol Biol Rev. 1997 Sep;61(3):377-92. |[2]Smee DF, et al. A review of compounds exhibiting anti-orthopoxvirus activity in animal models. Antiviral Res. 2003 Jan;57(1-2):41-52.|[3]Rand A, et al. Effect of levofloxacin on some body tissues in mice. Effect of levofloxacin on some body tissues in mice. Iraqi Journal of Veterinary Sciences, 2021.|[4]JI B, et al. In vitro and in vivo activities of levofloxacin against Mycobacterium tuberculosis. Antimicrob Agents Chemother. 1995 Jun;39(6):1341-4.
CAS Number
– 100986-85-4
Molecular Weight
– 361.37
Compound Purity
– 99.93
SMILES
– O=C(C(C1=O)=CN2[C@@H](C)COC3=C(N4CCN(C)CC4)C(F)=CC1=C23)O
Clinical Information
– Launched
Research Area
– Infection; Cancer
Solubility
– DMSO : 10 mg/mL (ultrasonic)|H2O : ≥ 5 mg/mL
Target
– Antibiotic;Bacterial;DNA/RNA Synthesis;Orthopoxvirus;Topoisomerase
Isoform
– Quinolone;Topoisomerase
Pathway
– Anti-infection;Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
