Products Details

Product Description

– LDHA-IN-5 is a novel, potent, dual GO/LDHA inhibitor for primary hyperoxaluria.

Web ID

– HY-115875

Shipping

– Room temperature

Applications

– Metabolism-sugar/lipid metabolism

Molecular Formula

– C27H22FN7O6S3

References

– [1]Ding J, et al. Dual Glycolate Oxidase/Lactate Dehydrogenase A Inhibitors for Primary Hyperoxaluria. ACS Med Chem Lett. 2021 May 20;12(7):1116-1123.

CAS Number

– 2776148-90-2

Molecular Weight

– 655.70

SMILES

– NS(=O)(C1=CC=C(C=C1F)CC2=C(N(N=C2C3=CC(SC4=C(N=NN4)C(O)=O)=CC=C3)C5=NC(C(O)=O)=CS5)CC6CC6)=O

Clinical Information

– No Development Reported

Research Area

– Metabolic Disease

Solubility

– 10 mM in DMSO

Target

– Lactate Dehydrogenase

Pathway

– Metabolic Enzyme/Protease

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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