LCH-7749944
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LCH-7749944

SKU T11826-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 72 CAD through 1,397 CAD

Products Details

Product Description

– LCH-7749944 (GNF-PF-2356) is a potent PAK4 inhibitor with an IC50 of 14.93 μM, effectively suppressing the proliferation of human gastric cancer cells by downregulating the PAK4/c-Src/EGFR/cyclin D1 pathway and inducing apoptosis.

Web ID

– T11826

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C20H22N4O2

References

– Zhang J, et al. LCH-7749944, a novel and potent p21-activated kinase 4 inhibitor, suppresses proliferation and invasion in human gastric cancer cells. Cancer Lett. 2012 Apr 1;317(1):24-32.

CAS Number

– 796888-12-5

Molecular Weight

– C20H22N4O2

Compound Purity

– 0.9928

SMILES

– COc1cccc(Nc2nc(NCC3CCCO3)c3ccccc3n2)c1

Target

– Others

Pathway

– Apoptosis|||Cytoskeletal Signaling

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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