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Products Details
Product Description
– LB244, a homologue of BB-Cl-amidine, functions as an orally effective STING inhibitor with an EC50 value of 0.8 μM, applicable in the treatment of STING-dependent inflammatory diseases. However, pharmacokinetic studies have shown that LB244 exhibits limited oral activity in mice [1].
Web ID
– T79730
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C30H27N5O5
Molecular Weight
– C30H27N5O5
SMILES
– O=C(N[C@@H](CCCCNC(C1=CC=C([N+]([O-])=O)O1)=O)C2=NC(C=CC=C3)=C3N2)C(C=C4)=CC=C4C5=CC=CC=C5
Pathway
– Immunology/Inflammation
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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