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Products Details
Product Description
– Lateritin is a potent inhibitor of acyl-CoA:cholesterol acyltransferase (ACAT), isolated from the mycelial cake of Gibberella lateritium IFO 7188[1]. Lateritin also inhibits the growth of a mini-panel of human cancer cell lines, gram-positive bacteria, and Candida albicans[2].
Web ID
– HY-121407
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C15H19NO3
References
– [1]K Hasumi, et al. Lateritin, a new inhibitor of acyl-CoA:cholesterol acyltransferase produced by Gibberella lateritium IFO 7188. J Antibiot (Tokyo).1993 Dec;46(12):1782-7.|[2]Robin K Pettit, et al. Isolation of human cancer cell growth inhibitory, antimicrobial lateritin from a mixed fungal culture. Planta Med. 2010 Mar;76(5):500-1.
CAS Number
– 172721-98-1
Molecular Weight
– 261.32
SMILES
– O=C(O[C@@H]1C(C)C)[C@@H](CC2=CC=CC=C2)N(C)C1=O
Clinical Information
– No Development Reported
Research Area
– Infection; Cancer
Solubility
– 10 mM in DMSO
Target
– Acyltransferase
Pathway
– Metabolic Enzyme/Protease
Product type
– Natural Products
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
