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Products Details
Product Description
– Lateritin is a potent inhibitor of acyl-CoA:cholesterol acyltransferase (ACAT), isolated from the mycelial cake of Gibberella lateritium IFO 7188[1]. Lateritin also inhibits the growth of a mini-panel of human cancer cell lines, gram-positive bacteria, and Candida albicans[2].
Web ID
– HY-121407
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C15H19NO3
References
– [1]K Hasumi, et al. Lateritin, a new inhibitor of acyl-CoA:cholesterol acyltransferase produced by Gibberella lateritium IFO 7188. J Antibiot (Tokyo).1993 Dec;46(12):1782-7.|[2]Robin K Pettit, et al. Isolation of human cancer cell growth inhibitory, antimicrobial lateritin from a mixed fungal culture. Planta Med. 2010 Mar;76(5):500-1.
CAS Number
– 172721-98-1
Molecular Weight
– 261.32
SMILES
– O=C(O[C@@H]1C(C)C)[C@@H](CC2=CC=CC=C2)N(C)C1=O
Clinical Information
– No Development Reported
Research Area
– Infection; Cancer
Solubility
– 10 mM in DMSO
Target
– Acyltransferase
Pathway
– Metabolic Enzyme/Protease
Product type
– Natural Products
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