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Products Details
Product Description
– L82 is a DNA ligase 1 (DNA Lig1) inhibitor (hLig1 IC50=12 μM) that is selective and non-competitive.L82 expresses anti-proliferative activity against breast cancer cells.
Web ID
– T60753
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C11H8ClN5O4
References
– Howes TRL, et al. Structure-activity relationships among DNA ligase inhibitors: Characterization of a selective uncompetitive DNA ligase I inhibitor. DNA Repair (Amst). 2017;60:29-39.
CAS Number
– 329227-30-7
Molecular Weight
– C11H8ClN5O4
Compound Purity
– 0.99
SMILES
– Oc1ccc(C=NNc2cn[nH]c(=O)c2Cl)cc1[N+]([O-])=O
Pathway
– DNA Damage/DNA Repair
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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