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L2H2-6OTD
Products Details
Product Description
– L2H2-6OTD, containing one to four G-quadruplex binding loops, is a telomeric inhibitor analogue. l2H2-6OTD has telomerase inhibitory activity with an IC50 value of 15 nM[1].
Web ID
– HY-148200
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C30H30N10O8
References
– [1]Keisuke Iida, et al. Evaluation of the interaction between long telomeric DNA and macrocyclic hexaoxazole (6OTD) dimer of a G-quadruplex ligand. Molecules. 2013 Apr 12;18(4):4328-41.
CAS Number
– 1016263-75-4
Molecular Weight
– 658.62
SMILES
– NCCCC[C@H](NC(C1=COC(C2=COC3=N2)=N1)=O)C4=NC(C5=NC(C6=NC(C(N[C@H](C7=NC3=CO7)CCCCN)=O)=CO6)=CO5)=CO4
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Telomerase
Pathway
– Cell Cycle/DNA Damage
Product type
– Reference compound
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