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L-DABA (hydrobromide)
SKU
HY-101414A-100 mg
Category Reference compound
Tags Cancer; Neurological Disease, Endogenous Metabolite;GABA Receptor, Membrane Transporter/Ion Channel;Metabolic Enzyme/Protease;Neuronal Signaling
$50 – $80
Products Details
Product Description
– L-DABA (L-2,4-Diaminobutyric acid) hydrobromide is a week GABA transaminase inhibitor with an IC50 of larger than 500 μM; exhibits antitumor activity in vivo and in vitro.
Web ID
– HY-101414A
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture)
Shipping
– Room Temperature
Molecular Formula
– C4H11BrN2O2
References
– [1]Ronquist G, et al. Antitumor activity of L-2,4 diaminobuturic acid against mouse fibrosarcoma cells in vitro and in vivo. J Cancer Res Clin Oncol. 1980;96(3):259-68.|[2]Beart PM, et al. l-2,4-Diaminobutyric acid and the GABA system. Neurosci Lett. 1977 Jul;5(3-4):193-8.|[3]Panasci L, et al. The cytolytic effect of L-2,4 diaminobutyric acid with malignant glioma cells and fibroblasts. Cancer Chemother Pharmacol. 1988;21(2):143-4.
CAS Number
– 73143-97-2
Molecular Weight
– 199.05
Compound Purity
– 98.0
SMILES
– NCC[C@H](N)C(O)=O.[H]Br
Clinical Information
– No Development Reported
Research Area
– Cancer; Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Endogenous Metabolite;GABA Receptor
Pathway
– Membrane Transporter/Ion Channel;Metabolic Enzyme/Protease;Neuronal Signaling
Product type
– Reference compound
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