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KW-2478
Price range: 82 CAD through 1,115 CAD
Products Details
Product Description
– KW-2478 is a non-ansamycin HSP90 inhibitor with IC50 of 3.8 nM.
Web ID
– T6558
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C30H42N2O9
Citations
– 1. Zeng D, Gao M, Zheng R, et al. The HSP90 inhibitor KW-2478 depletes the malignancy of BCR/ABL and overcomes the imatinib-resistance caused by BCR/ABL amplification. Experimental Hematology & Oncology. 2022, 11(1): 1-14
2. Zeng D, Gao M, Zheng R, et al. The HSP90 inhibitor KW-2478 depletes the malignancy of BCR/ABL and overcomes the imatinib-resistance caused by BCR/ABL amplifcation. Experimental Hematology & Oncology. 2022, 11(1): 1-14
3. Li H J, Wang Q S, Han W, et al. Anti-NSCLC activity in vitro of Hsp90N inhibitor KW-2478 and complex crystal structure determination of Hsp90N-KW-2478. Journal of Structural Biology. 2021, 213(2): 107710.
References
– Takayuki Nakashima, et al. Clin Cancer Res, 2010, 16(10), 2792-2802.
CAS Number
– 819812-04-9
Molecular Weight
– C30H42N2O9
Compound Purity
– 0.9952
SMILES
– CCc1c(O)cc(O)c(C(=O)c2ccc(OCCN3CCOCC3)c(OC)c2)c1CC(=O)N(CCOC)CCOC
Pathway
– Cytoskeletal Signaling|||Metabolism
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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