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Kukoamine A
$152 – $503
Products Details
Product Description
– Kukoamine A is a natural occurring spermine derivative, acts as a potent inhibitor of trypanothione reductase (Ki, 1.8 μM), with antihypertensive activity[1].
Web ID
– HY-N2392
Storage Temperature
– -20°C, 3 years (Powder)
Shipping
– Blue Ice
Applications
– COVID-19-immunoregulation
Molecular Formula
– C28H42N4O6
References
– [1]Ponasik JA, et al. Kukoamine A and other hydrophobic acylpolyamines: potent and selective inhibitors of Crithidia fasciculata trypanothione reductase. Biochem J. 1995 Oct 15;311 ( Pt 2):371-5.
CAS Number
– 75288-96-9
Molecular Weight
– 530.66
Compound Purity
– 99.49
SMILES
– O=C(NCCCNCCCCNCCCNC(CCC1=CC=C(O)C(O)=C1)=O)CCC2=CC=C(O)C(O)=C2
Clinical Information
– No Development Reported
Research Area
– Infection; Cardiovascular Disease
Solubility
– DMSO : 100 mg/mL (ultrasonic)|H2O : 125 mg/mL (ultrasonic)
Target
– Parasite
Isoform
– Trypanosoma
Pathway
– Anti-infection
Product type
– Natural Products
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
