KU 59403
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KU 59403

SKU T15673-25 mg Category Brand:

Price range: 1,411 CAD through 2,832 CAD

Products Details

Product Description

– KU 59403 is a selective and potent ATM inhibitor with antitumor and anticancer activity, inhibits ATM, DNA-PK and PI3K, and is often used in combination therapy with PARP or ATR inhibitors to slow the progression of cancer.

Web ID

– T15673

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C29H32N4O4S2

References

– Batey MA, et al. Preclinical evaluation of a novel ATM inhibitor, KU59403, in vitro and in vivo in p53 functional and dysfunctional models of human cancer. Mol Cancer Ther. 2013 Jun;12(6):959-67.

CAS Number

– 845932-30-1

Molecular Weight

– C29H32N4O4S2

Compound Purity

– 0.991

SMILES

– CN1CCN(CCC(=O)Nc2ccc3Sc4c(Sc3c2)cccc4-c2cc(=O)cc(o2)N2CCOCC2)CC1

Target

– Autophagy|||Ras

Pathway

– PI3K/Akt/mTOR signaling|||DNA Damage/DNA Repair

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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