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Products Details
Product Description
– KRAS G12D modulator-1 (compound 6) is a potent KRAS G12D modulator with IC50 values of 1-10 μM for NEA-G12D, PPI-G12D, and p ERK-AGS, respectively. KRAS G12D modulator-1 can be used in research of cancer[1].
Web ID
– HY-153555
Shipping
– Room temperature
Molecular Formula
– C30H36FN5O4
References
– [1]Hong L, et, al. Kras modulators and uses thereof. WO2022261210.
CAS Number
– 2883034-05-5
Molecular Weight
– 549.64
SMILES
– OC1=CC(C=CC=C2)=C2C(N3CC4=NC(OC[C@@]56N(CCC6)C[C@@H](C5)F)=NC(N7C[C@@H](C[C@H](C7)O)O)=C4CC3)=C1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Ras
Pathway
– GPCR/G Protein
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
