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Products Details
Product Description
– KPH2f is a safe, orally active, and effective dual URAT1/GLUT9 inhibitor with IC50s of 0.24 μM and 9.37 μM for URAT1 and GLUT9, respectively. KPH2f shows little effects on OAT1 and ABCG2 (IC50=32.14 and 26.74 μM)[1].
Web ID
– HY-144305
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C24H16N3NaO2S
References
– [1]Zhao Z, et al. Discovery of novel verinurad analogs as dual inhibitors of URAT1 and GLUT9 with improved Druggability for the treatment of hyperuricemia. Eur J Med Chem. 2022;229:114092.
CAS Number
– 2760615-09-4
Molecular Weight
– 433.46
SMILES
– N#CC1=C2C=CC=CC2=C(C=C1)NC3=C(C=CN=C3)SCC4=CC=CC=C4C(O[Na])=O
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– GLUT;URAT1
Pathway
– Membrane Transporter/Ion Channel
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
