Products Details

Product Description

– Kolavenic acid analog (KAA) is an anticancer agent. Kolavenic acid analog shows strong activity against HSET-overproducing yeast cells. Kolavenic acid analog inhibits centrosome clustering in human cancer cells containing high HSET levels and supernumerary centrosomes[1].

Web ID

– HY-146146

Shipping

– Room temperature

Applications

– Cancer-programmed cell death

Molecular Formula

– C25H38O4

References

– [1]Kurisawa N, et al. Kolavenic acid analog restores growth in HSET-overproducing fission yeast cells and multipolar mitosis in MDA-MB-231 human cells. Bioorg Med Chem. 2020 Jan 1;28(1):115154.

CAS Number

– 2379777-37-2

Molecular Weight

– 402.57

SMILES

– O=C(O)/C=C(C)/CC[C@]1(C)[C@H](C)C[C@@H](OC(/C(C)=C/C)=O)[C@@]2(C)C(C)=CCC[C@@]12[H]

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– 10 mM in DMSO

Target

– Kinesin

Pathway

– Cell Cycle/DNA Damage;Cytoskeleton

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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