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Products Details
Product Description
– Kolavenic acid analog (KAA) is an anticancer agent. Kolavenic acid analog shows strong activity against HSET-overproducing yeast cells. Kolavenic acid analog inhibits centrosome clustering in human cancer cells containing high HSET levels and supernumerary centrosomes[1].
Web ID
– HY-146146
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C25H38O4
References
– [1]Kurisawa N, et al. Kolavenic acid analog restores growth in HSET-overproducing fission yeast cells and multipolar mitosis in MDA-MB-231 human cells. Bioorg Med Chem. 2020 Jan 1;28(1):115154.
CAS Number
– 2379777-37-2
Molecular Weight
– 402.57
SMILES
– O=C(O)/C=C(C)/CC[C@]1(C)[C@H](C)C[C@@H](OC(/C(C)=C/C)=O)[C@@]2(C)C(C)=CCC[C@@]12[H]
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Kinesin
Pathway
– Cell Cycle/DNA Damage;Cytoskeleton
Product type
– Reference compound
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