Download Files:
Ketoconazole
Price range: 53 CAD through 587 CAD
Products Details
Product Description
– Ketoconazole (R-41400), a CYP3A4 inhibitor, is an imidazole anti-fungal agent.
Web ID
– T0679
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C26H28Cl2N4O4
Citations
– 1. Yu H, Song M, Hu K, et al. Influence of Bisphenol Compounds at Nanomolar Concentrations on Chromosome Damage Induced by Metabolically Activated Carcinogens in HepG2 Cells. Environmental Science & Technology. 2021
2. Yu H, Chen Z, Hu K, et al. Potent Clastogenicity of Bisphenol Compounds in Mammalian Cells—Human CYP1A1 Being a Major Activating Enzyme. Environmental Science & Technology. 2020, 54(23): 15267-15276.
3. Song M, Wang Y, Chen Z, et al. Human CYP enzyme-activated genotoxicity of 2, 2′, 4, 4′-tetrabromobiphenyl ether in mammalian cells. Chemosphere. 2021: 132784.
4. Ren L, Li W, Zheng X, et al. Benzimidazoles induce concurrent apoptosis and pyroptosis of human glioblastoma cells via arresting cell cycle. Acta Pharmacologica Sinica. 2021: 1-15.
5. Xu J, Liu R, Sun F, et al. Eucalyptal D Enhances the Antifungal Effect of Fluconazole on Fluconazole-Resistant Candida albicans by Competitively Inhibiting Efflux Pump. Frontiers in Cellular and Infection Microbiology. 2019, 9
6. Zhou L, Tian M, Zhang B, et al.Lysosome targeting fluorescent probe for NAAA imaging and its applications in the drug development for anti-inflammatory.International Journal of Biological Macromolecules.2024: 130307.
References
– Oliver WR Jr, et al. Proc Natl Acad Sci U S A, 2001, 98(9), 5306-5311.
CAS Number
– 65277-42-1
Molecular Weight
– C26H28Cl2N4O4
Compound Purity
– 0.9961
SMILES
– C([C@]1(O[C@@H](COC2=CC=C(C=C2)N3CCN(C(C)=O)CC3)CO1)C4=C(Cl)C=C(Cl)C=C4)N5C=CN=C5
Target
– Others
Pathway
– Microbiology/Virology|||GPCR/G Protein|||Metabolism|||Immunology/Inflammation|||MAPK
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
Related Products
1000 in stock
1000 in stock
