KDOAM-25
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KDOAM-25

SKU T11751-25 mg Category Brand:

Price range: 2,590 CAD through 4,000 CAD

Products Details

Product Description

– KDOAM-25, a potent and highly selective inhibitor of histone lysine demethylases 5 (KDM5) with IC50 values of 71 nM for KDM5A, 19 nM for KDM5B, 69 nM for KDM5C, and 69 nM for KDM5D, enhances global H3K4 methylation at transcriptional start sites and reduces proliferation in multiple myeloma MM1S cells.

Web ID

– T11751

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C15H25N5O2

References

– Tumber A, et al. Potent and Selective KDM5 Inhibitor Stops Cellular Demethylation of H3K4me3 at Transcription Start Sites and Proliferation of MM1S Myeloma Cells. Cell Chem Biol. 2017 Mar 16;24(3):371-380.

CAS Number

– 2230731-99-2

Molecular Weight

– C15H25N5O2

SMILES

– C(NCC(N(CCN(C)C)CC)=O)C1=CC(C(N)=O)=CC=N1

Target

– Others

Pathway

– Microbiology/Virology

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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