Kaempferol

SKU T2177-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 53 CAD through 462 CAD

Products Details

Product Description

– Kaempferol (Robigenin) is a natural flavonoid and an inverse agonist of ERRα and ERRγ. Kaempferol has a wide range of antitumor, anti-inflammatory, antioxidant, antibacterial and antiviral activities.

Web ID

– T2177

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C15H10O6

Citations

– 1. Wang R, Deng Z, Zhu Z, et al.Kaempferol promotes non-small cell lung cancer cell autophagy via restricting Met pathway.Phytomedicine.2023: 155090. 2. Shao Y, Tang B, Ding Y, et al.Kaempferide ameliorates cisplatin-induced nephrotoxicity via inhibiting oxidative stress and inducing autophagy.Acta Pharmacologica Sinica.2023: 1-13. 3. Shan H, Zhang X, Mi Y, et al.Eriodictyol Suppresses Gastric Cancer Cells via Inhibition of PI3K/AKT Pathway.Pharmaceuticals.2022, 15(12): 1477. 4. Shim K S, Hwang Y H, Jang S A, et al.  Water Extract of Lysimachia christinae Inhibits Trabecular Bone Loss and Fat Accumulation in Ovariectomized Mice. Nutrients. 2020, 12(7): 1927 5. Hwang Y H, Jang S A, Kim T, et al. Anti-osteoporotic and Anti-adipogenic Effects of Rhus chinensis Nutgalls in Ovariectomized Mice Fed with a High-fat Diet. Planta Medica. 2019, 85(14/15): 1128-1135 6. Jang S A, Hwang Y H, Yang H, et al. Ethanolic extract of Pyrrosia lingua (Thunb.) Farw. ameliorates OVX-induced bone loss and RANKL-induced osteoclastogenesis. Biomedicine & Pharmacotherapy. 2022, 147: 112640. 7. Shan H, Zhang X, Mi Y, et al.Eriodictyol Suppresses Gastric Cancer Cells via Inhibition of PI3K/AKT Pathway.Pharmaceuticals.2022, 15(12): 1477. 8. Zhang Y, Yu F, Hao J, et al. Study on the Effective Material Basis and Mechanism of Traditional Chinese Medicine Prescription (QJC) Against Stress Diarrhea in Mice. Frontiers in Veterinary Science. 2021, 8. 9. Lee S J, Yang H, Kim S C, et al.Ethanol Extract of Radix Asteris Suppresses Osteoclast Differentiation and Alleviates Osteoporosis.International Journal of Molecular Sciences.2023, 24(22): 16526. 10. Du Y Y, Sun T, Yang Q, et al.Therapeutic Potential of Kaempferol against Sleep Deprivation-Induced Cognitive Impairment: Modulation of Neuroinflammation and Synaptic Plasticity Disruption in Mice.ACS Pharmacology & Translational Science.2023

References

– Zhu L, et al. Kaempferol Suppresses Proliferation and Induces Cell Cycle Arrest, Apoptosis, and DNA Damage in Breast Cancer Cells. Oncol Res. 2019 Jun 21;27(6):629-634.

CAS Number

– 520-18-3

Molecular Weight

– C15H10O6

Compound Purity

– 0.9941

SMILES

– O=C1C=2C(OC(=C1O)C3=CC=C(O)C=C3)=CC(O)=CC2O

Pathway

– Apoptosis|||Proteases/Proteasome|||Endocrinology/Hormones|||Microbiology/Virology|||Metabolism|||Autophagy

Product type

– Natural Product

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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