K145 hydrochloride
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K145 hydrochloride

SKU TQ0138-5 mg Category Brand:

Price range: 80 CAD through 216 CAD

Products Details

Product Description

– K145 hydrochloride is a selective sphk2 inhibitor with substrate competitiveness and oral activity, with IC50 of 4.3 µM and Ki of 6.4 µM. K145 hydrochloride can induce apoptosis and has strong antitumor activity.

Web ID

– TQ0138

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C18H25ClN2O3S

Citations

– 1. Zhang L, Yi Y, Wang T, et al.25-Hydroxycholesterol inhibits classical swine fever virus entry into porcine alveolar macrophages by depleting plasma membrane cholesterol.Veterinary Microbiology.2023: 109668.

References

– Liu K, et al. Biological characterization of 3-(2-amino-ethyl)-5-[3-(4-butoxyl-phenyl)-propylidene]-thiazolidine-2,4-dione (K145) as a selective sphingosine kinase-2 inhibitor and anticancer agent. PLoS One. 2013;8(2):e56471.

CAS Number

– 1449240-68-9

Molecular Weight

– C18H25ClN2O3S

Compound Purity

– 0.9909

SMILES

– Cl.CCCCOc1ccc(CCC=C2/SC(=O)N(CCN)C2=O)cc1

Pathway

– GPCR/G Protein|||Apoptosis

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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