Products Details

Product Description

– JTK-853 is a novel, non-nucleoside Hepatitis C Virus (HCV) polymerase inhibitor which shows effective antiviral activity in HCV replicon cells with EC50s of 0.38 and 0.035 µM in genotype 1a H77 and 1b Con1 strains, respectively.

Web ID

– HY-19921

Shipping

– Room temperature

Applications

– COVID-19-anti-virus

Molecular Formula

– C28H23F7N6O4S2

References

– [1]Ando I, et al. JTK-853, a novel non-nucleoside hepatitis C virus polymerase inhibitor, demonstrates a high genetic barrier to resistance in vitro. Intervirology. 2013;56(5):302-9.

CAS Number

– 954389-09-4

Molecular Weight

– 704.64

SMILES

– O=C([C@@H]1N(S(=O)(C2=CC=C(C(F)(F)F)C=C2)=O)CCN(C3=NC4=NC(C5CC5)=NC=C4S3)C1)NCC6=CC=C(OC(F)(F)F)C(F)=C6

Clinical Information

– Phase 1

Research Area

– Infection

Solubility

– 10 mM in DMSO

Target

– HCV

Pathway

– Anti-infection

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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