Download Files:
Products Details
Product Description
– JNK-IN-11 (compound 1) is a potent JNK inhibitor with an IC50 value of 2.2, 21.4, 1.8 µM for JNK1, JNK2, JNK3, respectively. JNK-IN-11 has the potential for the research of alzheimer and parkinson disease[1].
Web ID
– HY-150053
Shipping
– Room temperature
Applications
– Neuroscience-Neurodegeneration
Molecular Formula
– C12H11NO3S2
References
– [1]Hom RK, et al. Design and synthesis of disubstituted thiophene and thiazole based inhibitors of JNK. Bioorg Med Chem Lett. 2010 Dec 15;20(24):7303-7.
CAS Number
– 676594-38-0
Molecular Weight
– 281.35
SMILES
– O=C(C1=C(NC(CC2=CC=CS2)=O)C=CS1)OC
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– JNK
Isoform
– JNK1;JNK2;JNK3
Pathway
– MAPK/ERK Pathway
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
