JNJ-38877618
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JNJ-38877618

SKU T15617-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 91 CAD through 1,856 CAD

Products Details

Product Description

– JNJ-38877618 (OMO-1) is an effective and highly selective inhibitor of Met kinase (IC50s: 2 and 3 nM for wild type and mutant Met, respectively).

Web ID

– T15617

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C20H12F2N6

References

– Libouban M, et al. OMO-1, a potent, highly selective, orally bioavailable, Met kinase inhibitor with a favorable preclinical toxicity profile, shows both monotherapy activity, against Met pathway-driven tumors, and EGFR TKI combination activity in acquired resistance models [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2018; 2018 Apr 14-18; Chicago, IL. Philadelphia (PA): AACR; Cancer Res 2018;78(13 Suppl):Abstract nr 4791.

CAS Number

– 943540-74-7

Molecular Weight

– C20H12F2N6

Compound Purity

– 0.9952

SMILES

– FC(F)(c1nnc2ccc(nn12)-c1ccncc1)c1ccc2ncccc2c1

Target

– Others

Pathway

– Tyrosine Kinase/Adaptors

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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