JNJ-10311795
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JNJ-10311795

SKU T27660-1 mg Category Brand:

Price range: 469 CAD through 3,168 CAD

Products Details

Product Description

– JNJ-10311795 (RWJ-355871) is a potent dual inhibitor of neutrophil elastase (Ki = 38 nM) and mast cell chymase (Ki = 2.3 nM) with significant anti-inflammatory activity, useful for studying pneumonia.

Web ID

– T27660

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C40H35N2O6P

References

– Maryanoff BE, de Garavilla L, Greco MN, Haertlein BJ, Wells GI, Andrade-Gordon P, Abraham WM. Dual inhibition of cathepsin G and chymase is effective in animal models of pulmonary inflammation. Am J Respir Crit Care Med. 2010 Feb 1;181(3):247-53. doi: 10.1164/rccm.200904-0627OC. Epub 2009 Oct 29. PubMed PMID: 19875688.

CAS Number

– 518062-14-1

Molecular Weight

– C40H35N2O6P

Compound Purity

– 0.9919

SMILES

– O=C(C=1C=CC=2C=CC=CC2C1)N3CCC(N(C(=O)C4=CC=5C=CC=CC5C=C4C(=O)C(C6=CC=CC=7C=CC=CC76)P(=O)(O)O)C)CC3

Pathway

– Proteases/Proteasome

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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