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JJH260
$210 – $5,200
Products Details
Product Description
– JJH260 is AIG1inhibitor, and inhibit the fluorophosphonate reactivity and fatty acid esters of hydroxy fatty acid (FAHFA) hydrolysis activity of AIG1in HEK293T cells, with IC50 values of 0.50 μM and 0.57 μM, respectively[1].
Web ID
– HY-116895
Storage Temperature
– -20°C, 3 years (Powder)
Shipping
– Blue Ice
Applications
– Metabolism-sugar/lipid metabolism
Molecular Formula
– C29H34ClN5O5
References
– [1]Xinkang Wang, et al. Antithrombotic Effects of the Novel Small-Molecule Factor XIa Inhibitor Milvexian in a Rabbit Arteriovenous Shunt Model of Venous Thrombosis. TH Open. 2023 Apr; 7(2): e97–e104.|[2]William H Parsons, et al. AIG1 and ADTRP are atypical integral membrane hydrolases that degrade bioactive FAHFAs. Nat Chem Biol. 2016 May;12(5):367-372.
CAS Number
– 1831135-30-8
Molecular Weight
– 568.06
Compound Purity
– 98.05
SMILES
– CN(C1=CC=C(C(N2CCN(C3C2)C(N(C3=O)OC(N4CCC(CC4)CCC5=CC=C(C=C5)Cl)=O)=O)=O)C=C1)C
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease
Solubility
– DMSO : 6.25 mg/mL (ultrasonic)
Target
– Androgen Receptor;MAGL
Pathway
– Metabolic Enzyme/Protease;Vitamin D Related/Nuclear Receptor
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
