JJH260

SKU T38107-1 mg Category Brand:

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Products Details

Product Description

– JJH260 is an N-hydroxy hydantoin carbamate that inhibits androgen-induced gene 1 (AIG1), an enzyme that hydrolyzes fatty acid esters of hydroxy fatty acids (FAHFAs). It blocks the hydrolysis of 9-PAHSA with an IC50 value of 0.57 μM. JJH260 also inhibits the novel FAHFA hydrolase androgen-dependent TFPI-regulating protein (ADTRP; IC50 = 8.5 μM), as well as the serine hydrolase ABHD6 and the lysophospholipases LYPLA1 and LYPLA2. JJH260 inhibits the FAHFA hydrolase activity of LNCaP and T cell lysates and intact cells.

Web ID

– T38107

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C29H34ClN5O5

CAS Number

– 1831135-30-8

Molecular Weight

– C29H34ClN5O5

SMILES

– O=C1C2N(C(=O)N1OC(=O)N3CCC(CCC4=CC=C(Cl)C=C4)CC3)CCN(C(=O)C5=CC=C(N(C)C)C=C5)C2

Pathway

– Others

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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