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JH-II-127
Price range: 72 CAD through 1,086 CAD
Products Details
Product Description
– JH-II-127 is an oral inhibitor of leucine-rich repeat kinase 2 (LRRK2), targeting WT LRRK2, G2019S LRRK2, and A2016T LRRK2 with IC50 values of 6.6 nM, 2.2 nM, and 47.7 nM, respectively.
Web ID
– T7155
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C19H21ClN6O3
References
– Discovery of a Pyrrolopyrimidine (JH-II-127), a Highly Potent, Selective, and Brain Penetrant LRRK2 Inhibitor[J]. ACS Medicinal Chemistry Letters, 2015, 6(5):584-589.
CAS Number
– 1700693-08-8
Molecular Weight
– C19H21ClN6O3
Compound Purity
– ≥98%
SMILES
– CNc1nc(Nc2ccc(cc2OC)C(=O)N2CCOCC2)nc2[nH]cc(Cl)c12
Pathway
– Autophagy
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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