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JG-23
$448 – $1,031
Products Details
Product Description
– JG-23 is a 4-chloro modified analog with ability to promote t-tau degradation. JG-23 exhibits good metabolic stability with a long T1/2 value (36 min) in mouse liver microsome assays[1].
Web ID
– HY-153822
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C19H16ClN3OS2
References
– [1]Shao H, et al. Inhibitors of heat shock protein 70 (Hsp70) with enhanced metabolic stability reduce tau levels. Bioorg Med Chem Lett. 2021 Jun 1;41:128025.
CAS Number
– 2640819-75-4
Molecular Weight
– 401.93
Compound Purity
– 99.64
SMILES
– CN1/C(SC2=CC=C(Cl)C=C21)=C3C(N(/C(S/3)=C/C4=CC=NC=C4)CC)=O
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Tau Protein
Pathway
– Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
