Jervine
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Jervine

SKU T3363-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 102 CAD through 2,432 CAD

Products Details

Product Description

– The biological activity of Jervine (Jerwiny) is mediated via its interaction with the 7 passes transmembrane protein Smoothened. Jervine binds with and inhibits smoothened, which is an integral part of the Hedgehog signaling pathways. With smoothened inhibited, the GLI1 transcription cannot be activated and Hedgehog target genes cannot be transcribed.

Web ID

– T3363

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C27H39NO3

References

– ten Berge D, et al. Development. 2001, 128(15):2929-38.

CAS Number

– 469-59-0

Molecular Weight

– C27H39NO3

Compound Purity

– 0.996

SMILES

– [H][C@@]12NC[C@@H](C)C[C@H]1O[C@]1(CC[C@]3([H])C(C(=O)[C@@]4([H])[C@@]3([H])CC=C3C[C@@H](O)CC[C@]43C)=C1C)[C@@H]2C

Pathway

– Stem Cells|||GPCR/G Protein

Product type

– Natural Product

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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