JCN037
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JCN037

SKU T8431-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 54 CAD through 939 CAD

Products Details

Product Description

– JCN037 is potent, non-covalent and brain-penetrant inhibitor of EGFR(EGFR, p-wtEGFR and pEGFRvⅢ with IC50 of 2.49 nM, 3.95 nM, 4.48 nM , respectively).

Web ID

– T8431

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C16H11BrFN3O2

References

– Jonathan E. Tsang, et al. Development of a Potent Brain-Penetrant EGFR Tyrosine Kinase Inhibitor against Malignant Brain Tumors. ACS Med. Chem. Lett. 2020. May 1.

CAS Number

– 2305154-31-6

Molecular Weight

– C16H11BrFN3O2

Compound Purity

– 1

SMILES

– Fc1c(Br)cccc1Nc1ncnc2cc3OCCOc3cc12

Pathway

– Angiogenesis|||JAK/STAT signaling|||Tyrosine Kinase/Adaptors

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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