JC-171
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JC-171

SKU T38106-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 474 CAD through 475 CAD

Products Details

Product Description

– JC-171, a selective inhibitor of the NLRP3 inflammasome, effectively inhibits LPS/ATP-induced interleukin-1β (IL-1β) release from J774A.1 macrophages with an IC50 of 8.45 μM[1].

Web ID

– T38106

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C16H17ClN2O5S

References

– Chunqing Guo, et al. Development and Characterization of a Hydroxyl-Sulfonamide Analogue, 5-Chloro-N-[2-(4-hydroxysulfamoyl-phenyl)-ethyl]-2-methoxy-benzamide, as a Novel NLRP3 Inflammasome Inhibitor for Potential Treatment of Multiple Sclerosis. ACS Chem Neurosci. 2017 Oct 18;8(10):2194-2201.

CAS Number

– 2112809-98-8

Molecular Weight

– C16H17ClN2O5S

SMILES

– COc1ccc(Cl)cc1C(=O)NCCc1ccc(cc1)S(=O)(=O)NO

Pathway

– Others

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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