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Products Details
Product Description
– Jagged-1 (188-204) TFA(219127-21-6 free base) is a fragment of the JAG-1 protein. JAG-1 is Notch ligand, a peptide that is the most conspicuously expressed ligand in skin. JAG-1 induces epidermal maturation. Exposing submerged keratinocytes monolayers to JAG-1 with elevated calcium concentration produces stratification with loricrin expression and NF-alphaB activation.
Web ID
– TP1293
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C95H128F3N25O28S3
References
– Jundt F, et al. Jagged1-induced Notch signaling drives proliferation of multiple myeloma cells. Blood. 2004 May 1;103(9):3511-5.
Molecular Weight
– C95H128F3N25O28S3
Compound Purity
– 0.9948
SMILES
– O=C(O)C(F)(F)F.O=C(N[C@@H](CC(O)=O)C(N[C@@H](CC(O)=O)C(N[C@@H](CC1=CC=C(C=C1)O)C(N[C@@H](CC2=CC=C(C=C2)O)C(N[C@@H](CC3=CC=C(C=C3)O)C(NCC(N[C@@H](CC4=CC=CC=C4)C(NCC(N[C@@H](CS)C(N[C@@H](CC(N)=O)C(N[C@@H](CCCCN)C(N[C@@H](CC5=CC=CC=C5)C(N[C@@H](CS)C(N[C@@H](CCCNC(N)=N)C(N6[C@@H](CCC6)C(N[C@@H](CCCNC(N)=N)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CS)N
Pathway
– Neuroscience|||Stem Cells|||Proteases/Proteasome
Product type
– Peptide
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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