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IVMT-Rx-3
SKU
HY-156247-Get quote
Category Reference compound
Tags Cancer, Metabolic Enzyme/Protease;NF-κB, MMP;NF-κB
Products Details
Product Description
– IVMT-Rx-3 is a inhibitor of SDCBP targeting of the PDZ1 and PDZ2 Domains of MDA-9/Syntenin. IVMT-Rx-3 blocks MDA-9/Syntenin interaction with Src, reduces NF-κB activation, and inhibits MMP-2/MMP-9 expression. IVMT-Rx-3 inhibits Melanoma Metastasis[1]</sup.
Web ID
– HY-156247
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C69H90F3N13O24
References
– [1]Pradhan AK, et al. Dual Targeting of the PDZ1 and PDZ2 Domains of MDA-9/Syntenin Inhibits Melanoma Metastasis. Mol Cancer Ther. 2023;22(10):1115-1127.
Molecular Weight
– 1542.52
SMILES
– O=C(O)C(F)(F)F.O=C1N2N=C(N=C2NC3=C1CCC3)C(NC4=C(C=C(C(C)=C4)NC(CCOCCOCCOCCOCCOCCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(O)=O)C(C)C)=O)CC5=CC=C(C=C5)O)=O)CC6=CC=C(O)C=C6)=O)CCC(O)=O)=O)CC(N)=O)=O)[C@@H](C)O)=O)=O)C)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– MMP;NF-κB
Pathway
– Metabolic Enzyme/Protease;NF-κB
Product type
– Reference compound
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