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Products Details
Product Description
– ITX3 is a specific, non-toxic, active and selective TrioN RhoGEF inhibitor with IC50 of 76 μM. ITX3 has anticancer effects, inhibits trion mediated GTP exchange on RhoG and Rac1, inhibits NGF-mediated neurite growth in PC12 cells and REF52 fibroblast structure formation induced by trion.
Web ID
– T15602
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C22H17N3OS
References
– Bouquier N, Vignal E, Charrasse S, et al. A cell active chemical GEF inhibitor selectively targets the Trio/RhoG/Rac1 signaling pathway. Chem Biol. 2009;16(6):657-666.
CAS Number
– 347323-96-0
Molecular Weight
– C22H17N3OS
Compound Purity
– 0.9902
SMILES
– Cc1cc(C=c2sc3nc4ccccc4n3c2=O)c(C)n1-c1ccccc1
Target
– Others
Pathway
– Cell Cycle/Checkpoint
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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