(-)-Isocorypalmine

$120$385

Products Details

Product Description

– (-)-Isocorypalmine (Tetrahydrocolumbamine), isolated from the crude base fraction of Corydalis chaerophylla, is a dopamine receptor ligand[1]. Recombinant CYP719A21 displays strict substrate specificity and high affinity (Km=4.63 ± 0.71 μM) for (-)-Isocorypalmine[2].

Web ID

– HY-N0927

Storage Temperature

– 4°C (Powder, protect from light)

Shipping

– Room Temperature

Applications

– Neuroscience-Neuromodulation

Molecular Formula

– C20H23NO4

References

– [1]Shen XL, et al. Isolation and identification of tetrahydrocolumbamine as a dopamine receptor ligand from Polygala tenuifolia Willd. Yao Xue Xue Bao. 1994;29(12):887-890.|[2]Dang TT, et al. Cloning and characterization of canadine synthase involved in noscapine biosynthesis in opium poppy. FEBS Lett. 2014;588(1):198-204.

CAS Number

– 483-34-1

Molecular Weight

– 341.40

Compound Purity

– 99.38

SMILES

– OC(C=C1[C@@]2([H])N3CC4=C(C=CC(OC)=C4OC)C2)=C(C=C1CC3)OC

Clinical Information

– No Development Reported

Research Area

– Others

Solubility

– DMSO : ≥ 6.67 mg/mL

Target

– Dopamine Receptor

Pathway

– GPCR/G Protein;Neuronal Signaling

Product type

– Natural Products

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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