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Products Details
Product Description
– IRE1α kinase-IN-6 is a potent IRE1α inhibitor with an IC50 value of 4.4 nM.
Web ID
– HY-142659
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C25H23Cl2FN6O3S2
References
– [1]Beveridge RE, et al. Identification of BRaf-Sparing Amino-Thienopyrimidines with Potent IRE1α Inhibitory Activity. ACS Med Chem Lett. 2020 Oct 16;11(12):2389-2396.
CAS Number
– 2715123-88-7
Molecular Weight
– 609.52
SMILES
– FC(C(NS(=O)(C1=C(C=CC=C1)Cl)=O)=CC=C2Cl)=C2NC(C3=CSC(C3=NC=N4)=C4N[C@H]5CC[C@@H](CC5)N)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– IRE1
Pathway
– Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
