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IRE1α kinase-IN-6
1,552 CAD
Only 1000 item(s) left in stock.
Products Details
Product Description
– IRE1α kinase-IN-6 is a potent IRE1α inhibitor with an IC50 value of 4.4 nM.
Web ID
– T40336
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C25H23Cl2FN6O3S2
References
– Beveridge RE, et al. Identification of BRaf-Sparing Amino-Thienopyrimidines with Potent IRE1α Inhibitory Activity. ACS Med Chem Lett. 2020 Oct 16;11(12):2389-2396.
CAS Number
– 2715123-88-7
Molecular Weight
– C25H23Cl2FN6O3S2
SMILES
– N[C@H]1CC[C@@H](CC1)Nc1ncnc2c(csc12)C(=O)Nc1c(Cl)ccc(NS(=O)(=O)c2ccccc2Cl)c1F |wU:4.7,wD:1.0,(-4,-5.39,;-2.67,-4.62,;-1.33,-5.39,;,-4.62,;,-3.08,;-1.33,-2.31,;-2.67,-3.08,;1.33,-2.31,;1.33,-.77,;2.67,,;2.67,1.54,;1.33,2.31,;,1.54,;-1.46,2.02,;-2.37,.77,;-1.46,-.48,;;-1.94,3.48,;-.91,4.63,;-3.45,3.8,;-3.92,5.27,;-2.89,6.41,;-1.39,6.09,;-3.37,7.87,;-4.87,8.19,;-5.91,7.05,;-7.41,7.37,;-7.89,8.83,;-9.35,8.36,;-6.42,9.31,;-8.36,10.3,;-7.33,11.44,;-7.81,12.91,;-9.31,13.23,;-10.35,12.08,;-9.87,10.62,;-10.9,9.48,;-5.43,5.59,;-6.46,4.44,)|
Pathway
– Others
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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